Circulating levels of cholesterol in the blood play an important role in the health of an individual. High levels of total cholesterol and low-density lipoprotein (LDL, or 'bad') cholesterol increase your risk of developing heart disease and other cardiovascular-related diseases. However, high levels of high-density lipoprotein (HDL, or 'good') cholesterol act as a protective mechanism against heart and other cardiovascular-related diseases. The relationship between cholesterol levels and eye health are no exception. Perturbed cholesterol metabolism may play a role in age-related macular degeneration or retinal vein occlusion. Furthermore, cholesterol species form part of a greater lipid profile; circulating lipid species and lipid metabolism are essential aspects of eye health and disease. That said, an element of the Jiri Eye Study is measuring levels of total cholesterol, HDL cholesterol, and LDL cholesterol (empirically determined) in the serum of every individual participating in the study.
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